Séminaire Général de Physique

"Séminaire Général de Physique"

AMPHI PGG
(café à partir de 10h10)

A l'amphithéâtre Pierre-Gilles de Gennes
Bâtiment Condorcet, niveau -1

Prochain séminaire : Catherine Villard (LIED - UPC-CNRS) - Vendredi 21 juin 2024

Titre : Helical fungi under physical constraints

Résumé :

Helical filaments are represented in living organisms from the molecular to the multi-cellular scale. Described by Darwin in aerial and underground parts of plants as early as the 19th century, they still raise fundamental questions about their roles and their underlying mechanisms. We here focus on the helicity of the filaments (hyphae) of Fungi, taking as an example the fungus Candida albicans, an opportunistic pathogen of humans.
The question guiding us in the ANR HelPath project involving the Institut Pasteur (S.BB) and the Institut Charles Sadron in Strasbourg (Igor Kulic) is the link between virulence and helicity. I will present how this question has led us to use the concept of squeelix ("squeezedhelix") developed by Igor Kulic and coll. to understand and model the oscillatory behavior of hyphae under z confinement provided by microfluidic channels.
To evaluate the possible advantages of these oscillatory growth modalities in the colonization of complex environments, we also challenge the path finding properties of hyphae within micro-pillar arrays. Strikingly, hyphae use a logic pattern to invade such structured spaces, highlighting an elementary sense of proprioception in these filamentous organisms.

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Rendez-vous pour le café à partir de 10h10 :
Bâtiment Condorcet - Espace de convivialité du niveau -1 (en bas de l'escalier à vis)
10, rue Alice Domon et Léonie Duquet
Université Paris Cité - UFR de Physique Paris 13^ème

Pour les prochains Séminaires Généraux de Physique nous recevrons :